The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention
Purpose
The purpose of this study is to compare two different exercise programs to see if there are differences after exercise in fibromyalgia (FM) symptoms and responses from the immune system.
Condition
- Fibromyalgia
Eligibility
- Eligible Ages
- Between 18 Years and 70 Years
- Eligible Genders
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
for FM Patients: - Patients with a diagnosis of FM - Clearance from patient's physician to participate in a clinical trial - Not participating or willing to discontinue FM treatment with trans-cutaneous electrical nerve stimulation, biofeedback, tender-point injections, acupuncture, Yoga, and Tai Chi.
Exclusion Criteria
for all Participants: - Diagnosis of severe psychiatric illness - Abuse of alcohol, benzodiazepines, or other drugs - Active cardiovascular, pulmonary, hepatic, renal, gastrointestinal, or autoimmune disease (except Hashimoto's or Graves' disease that has been stable for 3 months before screening) - Current systemic infection - Active cancer (except basal cell carcinoma); - Unstable endocrine disease - Severe sleep apnea - Prostate enlargement or other genitourinary disorder (male patients) - Pregnancy or breastfeeding Inclusion Criteria for Healthy Controls: - Female - No apparent medical condition that will interfere with participation in the study - Not on any medication that will interfere with participation in this study Exclusion Criteria for Healthy Controls: - Medical or surgical conditions including medication that preclude participation in the study - Presence of motor or neuromuscular deficits that may preclude participating in fatigue exercise
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Arm Groups
Arm | Description | Assigned Intervention |
---|---|---|
Experimental Full mind-body exercises |
Participants will be trained to perform a type of mind-body exercise that involves low intensity exercise and body movements similar to Tai Chi. Participants will be asked to exercise 2 times per day for 8 weeks. |
|
Active Comparator Light mobility exercises: Control Group |
The Light mobility exercises group will perform a similar exercise as the experimental group. However without a few components. Participants will be asked to exercise two times per day for 8 weeks. |
|
No Intervention Healthy Controls |
Healthy females will be asked to make one visit to complete aerobic exercise test, questionnaires, and provide blood samples. |
|
Recruiting Locations
Kansas City, Kansas 66160
More Details
- Status
- Unknown status
- Sponsor
- University of Kansas Medical Center