Effects of Innovative Aerobic Exercise Training in Cystic Fibrosis

Purpose

This study will be a randomized controlled trial in patients with cystic fibrosis and conducted over a consecutive twelve-week period. A comparison standard of care group will be used as a control to an interventional exercise group. The study evaluates the effectiveness of standard of care therapy + exercise compared to standard of care only for improving cardiorespiratory-fitness in CF patients.

Condition

  • Cystic Fibrosis

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • diagnosed with Cystic Fibrosis - Prescribed and taking for 28 days ivacaftor-tezacaftor-elexacaftor (Trikafta) - 18 years and older

Exclusion Criteria

  • 17 years of age or less - not eligible for ivacaftor-tezacaftor-elexacaftor (Trikafta) - inability to exercise - pregnancy - status post lung transplantation - already participating in more than 150 minutes of aerobic exercise per week

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
exercise 		exercise prescription + standard of care
  • Behavioral: exercise
    partially supervised and home-based exercise activity
No Intervention
no exercise 		no exercise prescription + standard of care

Recruiting Locations

University of Kansas Medical Center
Kansas City, Kansas 66160
Contact:
Christine Morgan
913-588-1572
cmorgan6@kumc.edu

More Details

Status
Unknown status
Sponsor
University of Kansas Medical Center

Study Contact

Christine D Morgan, BA
913-588-1572
cmorgan6@kumc.edu