Hyperpolarized 129Xe MRI Lung Health Cohort

Purpose

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Condition

  • Healthy

Eligibility

Eligible Ages
Between 25 Years and 35 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Is enrolled in the American Lung Association Lung Health Cohort Study. - Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.

Exclusion Criteria

  • Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, > 140 cm shoulder circumference, dependent on weight distribution). - Is pregnant or breastfeeding - Oxygen saturation (SpO2) <88% on room air or with supplemental oxygen.

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Cross-Sectional

Recruiting Locations

University of Kansas Medical Center
Kansas City, Kansas 66160
Contact:
Cristal Monge
913-945-9399
chernandez@kumc.edu

More Details

Status
Recruiting
Sponsor
University of Kansas Medical Center

Study Contact

Adam Ruff
913-574-3932
aruff@kumc.edu