By doing this study, researchers hope to learn the effects of aerobic exercise on heart, lung, and bone health in people who cannot walk after a stroke.



Eligible Ages
Over 18 Years
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

  • Independent ambulation before stroke
  • Be able to understand and follow verbal commands in English
  • Have physicians' approval for exercise, and be in stable medical condition
  • Participant's first stroke
  • Unable to walk independently according to Functional Ambulation Category (FAC) (<2) after in-patient rehabilitation treatment
  • Between 6 weeks to 5 years after stroke onset

Exclusion Criteria

  • Current cardiovascular abnormalities other than stroke such as ischemic cardiovascular event or coronary artery bypass surgery less than 3 months ago
  • Musculoskeletal disorder which prevents subjects from participating in the exercise
  • Resting blood pressure more than 200/110 mm Hg
  • Current or previous pulmonary diseases in the past two years
  • Osteoporosis and restricted passive movement in the major joints of the lower limbs
  • Subjects will be excluded if they are unable to speak or understand English and/or unable to travel to the University of Kansas Medical Center (KUMC) Neuromuscular Research Laboratory

Study Design

Study Type
Intervention Model
Parallel Assignment
Primary Purpose
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Intervention Group
The intervention group will undergo an aerobic walking program using a treadmill, a body-weight support system, and an assistive device.
  • Behavioral: Aerobic walking program
    Participants will make 24 visits over an 8 week period, having 3 sessions per week. Each session will last about one hour.
Active Comparator
Control Group
The control group will receive standard physical therapy (PT).
  • Behavioral: Standard physical therapy
    Participants will receive standard care they normally would after a stroke.

Recruiting Locations

University of Kansas Medical Center
Kansas City, Kansas 66160

More Details

University of Kansas Medical Center

Study Contact

Abdulfattah Alqahtani


Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.