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Purpose

The purpose of this study is to determine the impact of a twice daily at-home olfactory training program with a twenty scent, essential oil-based smell test in patients with olfactory dysfunction.

Condition

Eligibility

Eligible Ages
Between 18 Years and 80 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Have clinical olfactory dysfunction

Exclusion Criteria

  • Pregnant women - Unable to perform routine follow-up - Current participation in another clinical trial during this trial - Patients with dementia, Alzheimer's disease, Parkinson's disease, or other neurocognitive disorders - Diagnosis of other systemic conditions known to impact the sinonasal cavity such as Wegener's granulomatosis, Churg Strauss, and immunodeficiency - Patients who are allergic to any of the smells or components of our olfactory testing - Chronic rhinosinusitis, malignant tumors and/or oncologic therapies (radiation/chemotherapy) - History of surgery on the nose or paranasal sinuses - Patients using medications that may impact olfactory function (i.e. corticosteroids)

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Group A: 15 Scents 		Participants will be asked to inhale 15 different scents two times a day.
  • Other: Smell Test
    Oils are used for each of the different scents. Each scent will be put on an aromatherapy inhaling stick.
Active Comparator
Group B: 4 Scents 		Participants will be asked to inhale 4 different scents two times a day.
  • Other: Smell Test
    Oils are used for each of the different scents. Each scent will be put on an aromatherapy inhaling stick.

More Details

Status
Completed
Sponsor
University of Kansas Medical Center

Study Contact

Detailed Description

This study randomizes participants to receive either a four scent or fourteen scent olfactory retraining protocol. Baseline olfaction will be tested with a currently commercially available smell test as well as an essential oil based smell test. The protocol involves twice daily retraining where the participant inhales the scent and makes a mental note of what they should be smelling. The training period is six months total with a visit at 3 months to re-assess smell function as well as at six months.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.