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Purpose

Pulmonary Artery Compliance measurements will be obtained with the Respirix device in patients with congestive heart failure decompensation. Echocardiogram, weight measurements, and BNP will also be gathered as independent measures of decompensation in the clinic. Pulmonary Artery Compliance measurements will be made daily during the hospital stay. Patients can continue using the device at home for the next 3 weeks. Each patient will serve as their own control and relative changes from their baseline will be recorded for each parameter.

Conditions

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  1. Patient must ≥ 18 years of age 2. Patient has been diagnosed with Congestive Heart Failure, class II-IV 3. Patient is currently being admitted for decompensation related to Congestive Heart Failure 4. Subject or subject's legally authorized representative is able to give informed consent before entering the study.

Exclusion Criteria

  1. Currently pregnant or breastfeeding 2. Clinical signs or symptoms of a respiratory infection 3. Unable to obtain a high-quality signal, as determined by variability of nPAC values throughout a single breath, within 48 hours of enrollment 4. Inability to withstand a 10 second end-inspiratory pause, in the opinion of the investigator 5. Deemed unsuitable for enrollment in study by the investigator based on subjects' history or physical examination

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Prevention
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Other
CardioSpire Device 		Patients blows into Respirix device or uses BIPAP machine for a few breaths solely to obtain signal.
  • Device: CardioSpire (Respirix) Device
    Patients will blow into the device through a small tube, which analyzes the signals in the airway patterns.

Recruiting Locations

University of Kansas
Kansas City, Kansas 66160
Contact:
Kyle Greening
kgreening2@kumc.edu

More Details

Status
Unknown status
Sponsor
Theranova, L.L.C.

Study Contact

Megan Nolte
4159268616
mnolte@theranova.com

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.