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Purpose

By doing this study, researchers hope to learn effects of Vit C on lumbar spine surgery outcomes.

Condition

Eligibility

Eligible Ages
Between 45 Years and 80 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients scheduled to have a lumbar spine fusion - Can read and understand the English language - BMI 35 or less

Exclusion Criteria

  • Patients taking certain medications - lumbar spine laminectomy or discectomy - taking a Vit C supplement - pregnancy - Cauda equine syndrome or spinal tumor - neurological, neurodegenerative or cognitive issues - renal pathology - sickle cell anemia - iron metabolism disorder

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Intervention Model Description
2 groups: placebo and Vitamin C
Primary Purpose
Treatment
Masking
Triple (Participant, Care Provider, Outcomes Assessor)
Masking Description
Blinded pilot randomized control trial

Arm Groups

ArmDescriptionAssigned Intervention
Active Comparator
Experimental 		Participants will receive Vit C tablets
  • Dietary Supplement: Vitamin C
    Daily use of Vit C tablets
Placebo Comparator
Placebo 		Participants will receive placebo tablets
  • Dietary Supplement: Placebo
    Daily use of placebo tablets

More Details

Status
Completed
Sponsor
University of Kansas Medical Center

Study Contact

Detailed Description

Lumbar spine surgeries are common procedures for management of low back pain and their prevalence is increasing. However, their outcomes are less than optimal. An effective and inexpensive solution to minimizing surgical complications and expediting recovery following lumbar spine surgery could be supplementation using high doses of vitamin C, also known as ascorbic acid. Vit C can help reduce oxidative stress and inflammation and improve immune system and body's own chemicals to fight pain. The researchers want to examine if Vit C is effective in decreasing pain and pain medications and improving function. Gaining a better understanding of effects of Vit C on patient recovery may lead to improved outcomes.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.