Vitamin C Supplement for Lumbar Spine Surgery
Purpose
By doing this study, researchers hope to learn effects of Vit C on lumbar spine surgery outcomes.
Condition
- Lumbar Spine Surgery
Eligibility
- Eligible Ages
- Between 45 Years and 80 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Patients scheduled to have a lumbar spine fusion - Can read and understand the English language - BMI 35 or less
Exclusion Criteria
- Patients taking certain medications - lumbar spine laminectomy or discectomy - taking a Vit C supplement - pregnancy - Cauda equine syndrome or spinal tumor - neurological, neurodegenerative or cognitive issues - renal pathology - sickle cell anemia - iron metabolism disorder
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Intervention Model Description
- 2 groups: placebo and Vitamin C
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Care Provider, Outcomes Assessor)
- Masking Description
- Blinded pilot randomized control trial
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Active Comparator Experimental |
Participants will receive Vit C tablets |
|
|
Placebo Comparator Placebo |
Participants will receive placebo tablets |
|
Recruiting Locations
Kansas City, Kansas 66160
Neena Sharma, PT, PhD, CMPT
More Details
- Status
- Unknown status
- Sponsor
- University of Kansas Medical Center
Detailed Description
Lumbar spine surgeries are common procedures for management of low back pain and their prevalence is increasing. However, their outcomes are less than optimal. An effective and inexpensive solution to minimizing surgical complications and expediting recovery following lumbar spine surgery could be supplementation using high doses of vitamin C, also known as ascorbic acid. Vit C can help reduce oxidative stress and inflammation and improve immune system and body's own chemicals to fight pain. The researchers want to examine if Vit C is effective in decreasing pain and pain medications and improving function. Gaining a better understanding of effects of Vit C on patient recovery may lead to improved outcomes.