University of Kansas Medical Center

Assessing the Utility of Ultrasound Compared to Cross-Sectional Imaging in the Follow-up of Patients With Renal Cell Carcinoma

Purpose

The aim of this study is to determine the utility of renal ultrasonography (US) in the detection of abdominal recurrences after definitive therapy for renal cell carcinoma (RCC) and compare the detection rate to that of cross-sectional imaging.

Condition

Renal Cell Carcinoma

Eligibility

Eligible Ages: Over 18 Years
Eligible Genders: All
Accepts Healthy Volunteers: No

Inclusion Criteria

Patients must be 18 year of age or older. - Patients having undergone radical or partial nephrectomy for the indication of renal cell carcinoma. - Most recent imaging study must have been either computed tomography (CT) or magnetic resonance imaging (MRI).

Exclusion Criteria

Patients with pT4 disease (tumor invades beyond the Gerota fascia: including contiguous extension into the ipsilateral adrenal gland). - Patients with metastatic disease prior to time of surgery requiring systemic treatment. - Patients with another active cancer diagnosis requiring systemic treatment. - Patients with contrast allergies. - Patients with baseline chronic kidney disease (GFR < 45 ml/min/1.73 m2).

Study Design

Phase: N/A
Study Type: Interventional
Allocation: N/A
Intervention Model: Single Group Assignment
Primary Purpose: Diagnostic
Masking: None (Open Label)
Masking Description: The sonographer for the additional ultrasound will be blinded as will be the blinded radiology who will compare the US to the most recent negative CT/MRI to determine if recurrence is visualized by US

Arm Groups

Arm	Description	Assigned Intervention
Experimental Ultrasonography	Patient will be scheduled to undergo an additional US by a blinded sonographer within 4 weeks of their most recent cross-sectional imaging that indicated a recurrence	Diagnostic Test: Ultrasonography Abdominal Ultrasonography

Recruiting Locations

University of Kansas Health System
Kansas City, Kansas 66160

More Details

Status: Unknown status
Sponsor: University of Kansas Medical Center

Study Contact

Katherine Glavin
913-588-8721
kglavin@kumc.edu

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.