Purpose

By doing this study, researchers hope to learn to see if there is relationship between whole egg consumption and brain choline status. Additionally, researchers also plan to see if there is a relationship between brain choline status and cognition.

Condition

Eligibility

Eligible Ages
Between 60 Years and 85 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Aged between 60 - 85 years of age - Good general health with no concomitant diseases - Cognitively normal as defined as Mini-mental state examination (MMSE) score ≥ 25 - BMI range: 20 - 40 kg/m2

Exclusion Criteria

  • Presence of central neurological disease (e.g., brain tumor, stroke, epilepsy, motor neuron disease, multiple sclerosis, Alzheimer's, Parkinson's) - Prior major head trauma with loss of consciousness - Presence of active unstable and life-threatening illness (e.g., cancer) - Presence of major psychiatric disorder within the past 3 years including depression, anxiety, and alcohol (over 3 drinks per day or total of 18 per week) or drug abuse (DSM-IV criteria; Geriatric Depression Score > 6) - Presence of diabetes mellitus or use of anti-diabetic agents - Use of psychoactive and investigational medications - Use of hormone replacement therapy - Tobacco smokers - Subjects with MRI contraindications

Study Design

Phase
Study Type
Observational
Observational Model
Ecologic or Community
Time Perspective
Cross-Sectional

Arm Groups

ArmDescriptionAssigned Intervention
Low Egg Consumers Participants who consume fewer than 1 whole egg per week
Moderate Egg Consumers Participants who consume 5-9 whole eggs per week
High Egg Consumers Participants who consumes great than or equal to 14 whole eggs per week

Recruiting Locations

University of Kansas Medical Center
Kansas City, Kansas 66160
Contact:
Aaron Smith, MS
913-229-5935
asmith71@kumc.edu

More Details

Status
Recruiting
Sponsor
University of Kansas Medical Center

Study Contact

Aaron Smith, MS
913-229-5935
asmith71@kumc.edu

Detailed Description

Participants will come to the research center for 2 different visits. Visit 1 will include anthropometric measurements, surveys, and a cognitive test. Approximately 7-10 days after visit 1, participants will come back to the research center for visit 2. At visit 2, participants will return surveys and a MRI scan will be performed to measure brain choline status. Potential participants need to be located within the Kansas City metro area.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.